Month: July 2024

I sent Hamilton Morris 16 x 250 mg capsules of our Church’s sacrament in May of 2022 for testing almost a year before the Promega/Usona Fungi Fiction article came out, after he had already been hired and provided equity shares by Compass Pathways, and offered him sacrament for analytical testing which he agreed to and personal bioassay which he declined not being a willing psychonaut.

Hamilton told me on an hour and a half long phone call three months ago that he was the source of the Promega/Usona samples and that he also sent those church sacrament samples to all the other labs who tested our sacrament like Kykeon Analytics Laboratory.

Hamilton said that he sent Promega/Usona two samples that were initially blinded to them. One sample was regular psilocybin mushrooms that Hamilton provided and the other sample was our sacrament according to Hamilton.

The defamatory Fungi Fiction article claims that the our sacramental mushrooms came from an anonymous church member when in fact they came directly from Hamilton Morris without the Church’s permission nor approval nor knowledge nor chain of custody for their authenticity or preservation.

We sent Hamilton another round of our sacrament in November of 2022 grown by a different grower. These were two 5 grams bags of two different strains of our sacrament: White Golden Teachers and Penis Envy psilocybin mushrooms fed 5-meo-dmt to the substrate.

Ben Moore and I upon receipt of the sacrament from our grower immediately successfully bioassayed the medicine along with other church members experiencing the telltale 5ht1a effect, without any 5ht2a effects. We then removed 5 grams from each bag and sent them to Hamilton.

Both times Hamilton used methanol only to attempt to extract the psilomethoxin and then analyze it using Mass Spectrometry. The first time he claims to have found only trace amounts of psilocin and tryptamine, finding no psilomethoxin nor psilomethoxin pro-drug psilomethoxcybin. The second time he claims to have found only ketamine and no psilocin or psilocybin nor psilomethoxin nor psilomethoxin pro-drug psilomethoxcybin.

Hamilton tested only one of the either White Golden Teachers or Penis Envy sacrament samples and never tested the other. He never shared any of either samples with any third party for testing to successfully replicate, corroborate and validate his results.

When Hamilton spoke with me he repeatedly told me that I should be suspicious of his corporate ties and that he was already working with Promega/Usona’s Alexander Sherwood on psilomethoxin and on psilomethoxin pro-drug psilomethoxcybin.

ChemRvix which published the Promega/Usona opinion piece clearly states: These are preliminary reports which have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health related behaviour, or be reported in news media as established information.

Additionally, the republishers did not conduct any investigative journalism of their own to verify the basis of the claims in Promega/Usona’s article nor conduct any additional testing to validate or disprove Promega/Usona’s claims. They did not provide the article with the following disclaimers:

This preliminary report should not be regarded as conclusive. It is inconclusive.
This preliminary report has not been peer-reviewed. It is inconclusive.
This preliminary report should not be reported in the news media as established information. It is inconclusive.
This preliminary report should not guide any health related behaviors like public safety that Promega/Usona claim are a potential risk with the Church’s sacrament.

Morris previously tested samples of the drug sent to him by the church in May 2022. Like Usona, he did not detect psilomethoxin but instead found trace amounts of psilocin before conducting another test in December of that year. On that occasion, he only detected ketamine, suggesting the church may have mishandled their sacrament. “I detected not even trace psilocin, but exclusively ketamine,” he says. Church leaders told Morris that they believe his tests failed to detect psilomethoxin because he used methanol for the extraction instead of water. “They said it’s not soluble in methanol,” Morris says. “That seems very unlikely.”

What Usona accomplished in layman’s terms is to feed laboratory synthesized 5-Me-DMT to the PsiH and PsiK enzymes that they extracted from Psilocbye Cubensis mushroom fruiting bodies grown on a substrate.  By combining the PsiH enzyme with 5-Me-DMT they were able to make 4-HO-5-Me-DMT and then by combining the PsiK enzyme they were able to turn 4-HO-5-Me-DMT in to 4-PO-5-Me-DMT aka 5-Methyl-Psilocbyin.

Comparatively speaking, the Church of the Sacred Synthesis makes Psilomethoxin (4-HO-5-MeO-DMT and Psilomethoxcybin (4-PO-5-MeO-DMT) by feeding laboratory synthesized 5-MeO-DMT from melatonin or mexamine to Psilocbye Cubensis mushroom substrate in the form of holy water that the substrate drinks to create our sacrament.  The 5-MeO-DMT combines with the PsiH enzyme in the mushroom mycelium to create 4-HO-5-MeO-DMT (Psilomethoxin) and the 4-HO-5-MeO-DMT then combines with the PsiK enzyme to make 4-HO-5-Meo-DMT (Psilomethoxcybin).

Usona’s 5-Methylpsilocbyin is a pro-drug that breaks down in vivo in rat and human into the active ingredient 5-Methylpsilocin which is 4-HO-5-Me-DMT.  Psilomethoxin is 4-HO-5-MeO-DMT.   The difference between psilomethoxin and the active ingredient in Promega’s 5-Methylpsilocbyin is only one Oxygen atom different.